Comprehensive evaluation of the premature birth in women with undifferentiated connective tissue dysplasia | Ukrainian Medical Journal

Ibadova T.V.,Maliar V.V.,Maliar V.A.,Maliar Vol.V.

Main
Publications
Comprehensive evaluation of the premature birth in women with undifferentiated connective tissue dysplasia

Comprehensive evaluation of the premature birth in women with undifferentiated connective tissue dysplasia

September 27, 2022

798

Obstetrics and Gynecology

Keywords :

contractile activity of the uterus,

isthmic-cervical insufficiency,

premature birth,

undifferentiated connective tissue dysplasia

Specialities :

Obstetrics and Gynecology

Resume

Preterm birth and related complications are the most significant cause of perinatal mortality and disability.

Aim: to assess the impact of undifferentiated connective tissue dysplasia (UCTD) on the course of the threat of premature birth.

Materials and methods. A clinical and instrumental study of the contractile activity of the uterus, isthmus area was carried out using hysterography, uterine tonus measurement, sonography and cervical resistometry.

Results. It has been established that the most objective idea of the clinical threat of premature birth in women with UCTD syndrome can be obtained by evaluating the contractile activity of the uterus and the condition of the isthmic-cervical area. It has been proven that the concept of providing assistance at the risk of premature birth in women with UCTD should be differentiated taking into account the activity of the uterus and the functional state of the isthmic-cervical area.

Conclusion. The basis of the pathogenesis of the threat of premature birth in women with UCTD syndrome is an isthmic-cervical insufficiency. For the purpose of early diagnosis of isthmic-cervical insufficiency on the background of dysplasia, a sonographic examination of the isthmic-cervical area in the dynamics of the gestational process should be carried out, starting from the early stages of pregnancy.

References

1. Гойда Н.Г. (2012) Стан репродуктивного здоров’я населення на межі тисячоліть. Журн. практ. лікаря, 5: 2–6.
2. Дворянский С.А. (2002) Преждевременные роды: пролонгирование недоношенной беременности, осложненной преждевременным излитием вод. Нижній Новгород, вид-во НГМА, 93 с.
3. Granese R., Gitto E., D’Angelo G. et al. (2019) Preterm birth: seven-year retrospective study in a single centre population. Ital. J. Pediatr., 45: 45. doi: 10.1186/s13052-019-0643-9.
4. Назаренко Л.Г., Руміех І.Х. (2010) Прогнозування цервікальної недостатності й втрати вагітності другого триместру. Здоб. клін. експеримент. мед., 1: 96–99.
5. McElroy S., Ilango S., Dimitrova A. et al. (2022) Extreme heat, preterm birth, and stillbirth: a global analysis across 14 lower-middle income countries. Env. Int., 158: 106902. doi: 10.1016/j.envint.2021.106902.
6. Жабченко І.А. (2018) Звичне невиношування: що необхідно робити і чого робити не слід. Здоров’я жінки, 1(127): 9–13. doi 10.15574/HW.2018.127.9.
7. Lawn J.E., Gravett M.G., Nunes T.M. et al.; the GAPPS Review Group (2010) Global report on preterm birth and stillbirth (1 of 7): defi nitions, description of the burden and opportunities to improve data. BMC Pregnancy and Childbirth. doi.org/10.1186/1471-2393-10-S1-S1.
8. zakon.rada.gov.ua/rada/show/v0624282-08#Text.
9. Васеленко В.А., Гордієнко І.Ю. (2005) Истмико-цервикальная недостаточность: все ещё клинико-диагностическая проблема? Ультразвукова перінатальна діагностика, 18: 21–30.
10. Маляр В.В. (2006) Комплексна оцінка та корекція активності матки при загрозі передчасних пологів. Автореф. дис. … канд. мед. наук, Львів, 20 с.
11. Brown R., Gagnon R., Delisle M.F. (2019) No. 373 — Cervical Insufficiency and Cervical Cerclage. J. Obstet. Gynaecol. Can., 41(2): 233–247. doi: 10.1016/j.jogc.2018.08.009.
12. Fotina E.V., Zakirova R.R., Alekseenkova M.V., Panina O.B. (2021) Connective tissue dysplasia in the genesis of cervical incompetence. Obst. Gynecol. Reproduct., 15(1): 41–50.
13. Гулиева З.С., Герасимов А.М. (2013) Недифференцированная дисплазия соединительной ткани как фактор риска развития невынашивания беременности в ранние сроки. Вест. Ивановской мед. акад., 18(2): 39–40.
14. Baker J.F., Ghio A.J. (2009) Iron homoeostasis in rheumatic disease. Rheumatology, 48(11): 1339–1344. doi.org/10.1093/rheumatology/kep221.
15. Воскресенский С.Л. (2004) Оценка состояния плода. Кардиотокография. Допплерометрия. Биофизический профиль. Учеб. пос. Книжный Дом, Минск, 304 с.