Cognitive dysfunction and hypertension: literature review and own experience

Peleshko O.S.; Skybchyk V.A.

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3 (131) – V/VI 2019 :

Original research

Cognitive dysfunction and hypertension: literature review and own experience

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Peleshko O.S.¹, Skybchyk V.A.²

Summary. The article summarizes available data linking arterial hypertension (AG) to cognitive dysfunction, dementia. In own study we also found that AG significantly increases the incidence of cognitive dysfunction in middle-aged persons (49.8±9.0 years). We selected 59 patients with AG of 2–3 degrees (the average level of systolic and diastolic blood pressure 166±13 and 97±6 mm Hg, respectively) (1st group) and 30 practically healthy individuals with normal level of blood pressure (2nd group). Neuropsychological examination was carried out by General Practitioner Assessment of Cognition (GPCOG), Mini-Mental State Examination (MMSE) and Schulte table. Significant cognitive decline was found in patients in the 1st group (MMSE 26.6±1.8, GPCOG 6.9±1.4, Schulte’s test 52.3±10.7; p<0.05). Such results correspond to mild and moderate cognitive dysfunction. There was no cognitive dysfunction in the 2nd group (MMSE 28.9±1.0, GPCOG 8.3±1.4, Schulte’s test 33.4±4.2).

DOI 10.32471/umj.1680-3051.131.142189

Published: 16.05.2019

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