Predictors of 18-month survival in patients with chronic heart failure and reduced left ventricular ejection fraction depending on gender
- 1SI «NSC «Institute of Cardiology named after MD Strazheska» NAMS of Ukraine, Kiev
- 2State Institution «National Science Center «Institute of Cardiology the name of academician M.D. Strazheskaya» NAMS of Ukraine», Kyiv
Summary. Aim — comparison of survival rates and predictors of the onset of lethal outcome in men and women with chronic heart failure (CHF) with reduced left ventricular ejection fraction (LV EF) during 18 month follow-up. Materials and methods. 356 patients with ischemic CHF and LV EF <40% were examined. Results. Analysis of survival in patients with CHF and reduced LV EF showed that cumulative survival at the end of 18 month of follow-up was not significantly different, and comprised 78 and 85% for men and women, respectively. Factors, associated with poor prognosis, varied significantly depending on gender. Predictors of lethal outcome during 18 months in men were: the presence of angina pectoris, right ventricle wall thickness, pulmonary artery average pressure, creatinine level, left ventricular end diastolic volume (LVEDV), left ventricular end systolic volume (LVESV), LVEDV index, LVESV index, estimated glomerular filtration rate, left ventricle free wall thickness end C-reactive protein level. There were determinate indicators with the most associated of poor prognosis of survival by cluster analysis. The main among them: left atrium >6.25 and 48 mmHg, size of left atrium >6.8 sm, size of the LVEF <17.5%, hemoglobin level
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