The effect of vitamin therapy on the course of chronic obstructive pulmonary disease in combination with iron-deficient conditions and with/without residual changes after cured pulmonary tuberculosis
Summary. Chronic obstructive pulmonary disease (COPD) is a widespread disease. In the conditions of the epidemic of pulmonary tuberculosis (PT), the number of people with residual changes after cured PT (RCPTs) is increases. All chronic diseases often lead to the development of iron deficiency states (IDS). However, we did not meet in literature the researches that studied the features of COPD/IDS in RCPTs patients and the effect on vitamin therapy (VT). We examined 71 patients with COPD and IDS, of which 38 were diagnosed with RCPTs. All patients before and after treatment were evaluated for clinical status, clinical examination, a study of respiratory function and determination of levels of anxiety and depression. It was found that among patients with COPD and COPD/RCPTs and existing IDS, which was included in the treatment regimen of VT compared with patients without using VT, there was more pronounced improvement according to clinical tests, increase of biochemical parameters (serum iron and percentage of saturation of transferrin by iron) and dynamic improvement in the psychological state, while forced expiratory volume-one second was likely to increase in patients who did not take VT. Also, the effect of pack-years of smoking on the course of the underlying disease when using VT is established.